Anti-ICOS (CD278) (Human) mAb-PE
Code | Size | Price |
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MBL-FP10896010 | 100 tests | £586.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: ISA-3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The ISA-3 monoclonal antibody specifically reacts with human CD278 or Inducible COStimulatory molecule (ICOS), a 47-60 kDA homodimeric glycoprotein also known as H4, AILIM, and CRP-1. It is expressed on activated T cells and a group of thymocytes and is involved in the proliferation, activation, and cytokine production of T cells. When plate-bound, the ISA-3 antibody induces the production of IL-4,5,10 in T cells.
Concentration:
5 uL (0.03 ug)/test
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
ICOS
References
Knapp, W., et al., Leukocyte typing IV. Oxford University Press (1989) Akbar, A. N., et al., J. Immunol. 140, 2171-2178 (1988) Smith, S. H., et al., Immunology. 58, 63-70 (1986)