Anti-PD-1 (CD279) (Human) mAb-FITC
| Code | Size | Price |
|---|
| MBL-FP10915002 | 25 tests | £277.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: MIH4
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.
Concentration:
5 uL (2 ug)/test
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
PD-1
References
Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Zhang, B., et al., Ann Rheum Dis. 67, 1037-1040 (2008) Chapel, A., et al., J Virol. 66, 3966-3970 (1992)