Anti-TIM3 (Human) mAb-APC
| Code | Size | Price |
|---|
| MBL-FP10978010 | 100 tests | £621.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: F38-2E2
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17. TIM3 can exist in soluble and membrane bound forms and the relevant ligand for the protein is Galectin-9. It plays a role in the creation of immunological tolerances, the secretion of Th1 and Th17 related cytokines, and HIV infection.
Concentration:
5 uL (0.06 ug)/test
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
TIM3
References
Hayashi, T., et al., Int J Exp Pathol. 86, 289-296 (2005) Lowenthal, J. W., et al., J Immunol. 134, 931-939 (1985) Huang, B., et al., Cancer Res. 67, 4346-4352 (2007)