Anti-IFN gamma (Human) mAb-FITC

MBL
Product Code: MBL-FP10995002
Product Group: Primary Antibodies
Supplier: MBL
CodeSizePrice
MBL-FP1099500225 tests£277.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 4S.B3
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C

Documents

Further Information

Background:
The 4S.B3 is a neutralizing antibody that binds with the human Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation
Concentration:
5 uL (0.5 ug)/test
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IFN gamma

References

Hayashi, T., et al., Int J Exp Pathol. 86, 289-296 (2005) Lowenthal, J. W., et al., J Immunol. 134, 931-939 (1985) Huang, B., et al., Cancer Res. 67, 4346-4352 (2007)