Anti-CD41 (Mouse) mAb-FITC
| Code | Size | Price |
|---|
| MBL-FP20135010 | 100 ug | £360.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: MWReg30
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The MWReg30 monoclonal antibody specifically reacts with mouse CD41, a transmembrane glycoprotein also known as integrin alpha 2b GPIIb. It is expressed on hematopoietic progenitors, megakaryocytes, and platelets. It forms a receptor with CD61 (integrin beta 3) that binds adhesion molecules such as fibrinogen, fibronectin, von Willebrand factor, and thrombin. Defects or absence of CD41 has been found to lead to coagulation disorders. The expression profile of CD150+,CD48-, and CD41- can be used to identify hematopoietic stem cells.
Concentration:
0.5 mg/mL
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD41
References
Cherukuri, A., et al., J Immunol. 167, 163-172 (2001) Krop, I., et al., Eur J Immunol. 26, 238-242 (1996) Engel, P., et al., Immunity. 3, 39-50 (1995) Sato, S., et al., Proc Natl Acad Sci U S A. 94, 13158-13162 (1997)