Anti-CD3 (Mouse) mAb Functional Grade
| Code | Size | Price |
|---|
| MBL-FP20192510 | 100 ug | £270.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: 17A2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD3
References
Abrams, J. S., et al., Immunol Rev. 127, 5-24 (1992) Cherwinski, H. M., et al., J Exp Med. 166, 1229-1244 (1987) Zhang, Y., et al., J Immunol. 181, 190-196 (2008)