Anti-CD25 (Mouse) mAb
| Code | Size | Price |
|---|
| MBL-FP20262010 | 100 ug | £215.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG1 λ
Antibody Clonality: Monoclonal
Antibody Clone: PC61.5
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD25
References
Marzio, R., et al., J Leukoc Biol. 62, 349-355 (1997) Yokoyama, W. M., et al., J Immunol. 141, 369-376 (1988) Sobel, E. S., et al., J Immunol. 150, 673-682 (1993)