Anti-B7-2 (CD86) (Mouse) mAb-PE
| Code | Size | Price |
|---|
| MBL-FP20326010 | 100 ug | £360.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: PO3.1
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The PO3.1 monoclonal antibody specifically reacts with CD86, also known as B7-2, a surface 80 kDa receptor and member of the B7 family. CD86 is a costimulatory molecule, expressed on B and T cells, dendritic cells, astrocytes, macrophages, Langerhans cells, and at a low level in newly explanted B and T lymphocytes. CD86 expression on B lymphocytes is upregulated by B-Cell Receptor complex, CD40 and certain cytokine receptors. CD80 (B7-1) and CD 86 (B7-2) are receptors for CD28 and CTLA-4, on the surface of T lymphocytes, enhancing the interactions between B and T cells.
Concentration:
0.2 mg/mL
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
B7-2
References
Fleming, T. J., et al., J Immunol. 151, 2399-2408 (1993) Daley, J. M., et al., J Leukoc Biol. 83, 64-70 (2008) Dietlin, T. A., et al., J Leukoc Biol. 81, 1205-1212 (2007)