Anti-CD19 (Mouse) mAb-FITC
| Code | Size | Price |
|---|
| MBL-FP20405050 | 500 ug | £423.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: 1D3
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.
Concentration:
0.5 mg/mL
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD19
References
Mechetner, E. B., & Roninson, I. B., Proc Natl Acad Sci U S A. 89, 5824-5828 (1992) Chaudhary, P. M., et al., Blood. 80, 2735-2739 (1992) Goda, K., et al., J Pharmacol Exp Ther. 320, 81-88 (2007)