Anti-Integrin alpha 2 (CD49b) (Mouse) Functional Grade
| Code | Size | Price |
|---|
| MBL-FP20422505 | 50 ug | £277.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: HMa2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1). VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
Integrin alpha 2
References
Ledbetter, J. A., & Herzenberg, L. A., Immunol Rev. 47, 63-90 (1979) Radrizzani, M., et al., J Neurosci Res. 42, 220-227 (1995) Seaman, W. E., et al., J Immunol. 130, 1713-1718 (1983)