Anti-Integrin alpha 4 (CD49d) (Mouse) Functional Grade

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MBL
Product Code: MBL-FP20432510
Product Group: Primary Antibodies
Supplier: MBL
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MBL-FP20432510100 ug£381.00
Quantity:
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Overview

Host Type: Rat
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: R1-2
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
4°C
Storage:
4°C

Documents

Further Information

Background:
The R1-2 monoclonal antibody specifically reacts with mouse CD49d (integrin alpha 4), which forms the VLA-4 complex with CD29 (integrin beta 1). VLA-4 is expressed on thymocytes, monocytes, and a subset of peripheral lymphocytes. It is the receptor for fibronectin and CD106 (VCAM-1). CD49d also forms a receptor for mucosal vascular addressin (MAdCAM-1) with integrin beta 7.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
Integrin alpha 4

References

Fleming, T. J., et al., J Immunol. 151, 2399-2408 (1993) Hestdal, K., et al., J Immunol. 147, 22-28 (1991) Huang, B., et al., Cancer Res. 67, 4346-4352 (2007)