Anti-Integrin alpha 4 (CD49d) (Mouse) Functional Grade
Code | Size | Price |
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MBL-FP20432550 | 500 ug | £603.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: R1-2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The R1-2 monoclonal antibody specifically reacts with mouse CD49d (integrin alpha 4), which forms the VLA-4 complex with CD29 (integrin beta 1). VLA-4 is expressed on thymocytes, monocytes, and a subset of peripheral lymphocytes. It is the receptor for fibronectin and CD106 (VCAM-1). CD49d also forms a receptor for mucosal vascular addressin (MAdCAM-1) with integrin beta 7.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
Integrin alpha 4
References
Fleming, T. J., et al., J Immunol. 151, 2399-2408 (1993) Hestdal, K., et al., J Immunol. 147, 22-28 (1991) Huang, B., et al., Cancer Res. 67, 4346-4352 (2007)