Anti-CD40 Ligand (CD154) (Mouse) mAb-Biotin
| Code | Size | Price |
|---|
| MBL-FP20483002 | 25 ug | £194.00 |
Quantity:
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Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: MR1
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
Concentration:
0.5 mg/mL
Conjugate:
Biotin
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
CD40 Ligand
References
Barclay, A. et al. , The leucocyte antigen factsbook, Academic Press (1997) Knapp W., et al., Leukocyte typing IV. Oxford University Press (1989) Sotiriou, S. N., et al., FASEB J. 20, 559-561 (2006)