Anti-c-Kit (CD117) (Mouse) mAb
| Code | Size | Price |
|---|
| MBL-FP20512010 | 100 ug | £284.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2b κ
Antibody Clonality: Monoclonal
Antibody Clone: ACK2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
c-Kit
References
Fleming, T. J., et al., J Immunol. 151, 2399-2408 (1993) Hestdal, K., et al., J Immunol. 147, 22-28 (1991) Huang, B., et al., Cancer Res. 67, 4346-4352 (2007)