Anti-IL-7Ra (CD127) (Mouse) mAb
Code | Size | Price |
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MBL-FP20522010 | 100 ug | £312.00 |
Quantity:
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Overview
Host Type: Rat
Antibody Isotype: IgG2a κ
Antibody Clonality: Monoclonal
Antibody Clone: A7R34
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Flow Cytometry
- Functional Study
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The A7R34 monoclonal antibody specifically reacts with the mouse CD127, the α subunit of the IL-7 receptor, expressed by immature B lymphocytes in the bone marrow, CD4-/CD8-, CD4+, and CD8+ thymocytes, and by mature T lymphocytes at low levels. Mature T cells express CD117 at low levels in the periphery.The A7R34 antibody prevents the interaction between IL-7 and its receptor and the binding of mAb SB/199, which also recognizes mouse CD127.
Concentration:
0.5 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IL-7Ra
References
Latz, E., et al., Nat Immunol. 5, 190-198 (2004) Leifer, C. A., et al., J. Immunol. 173, 1179-1183 (2004) J?zsef, L., et al., J. Immunol. 176, 1195-1202 (2006)