Anti-Notch3 (Mouse) mAb-APC
| Code | Size | Price |
|---|
| MBL-FP20678010 | 100 ug | £533.00 |
Quantity:
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Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: HMN3-133
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.
Concentration:
0.2 mg/mL
Conjugate:
APC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Notch3
References
Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Ritz, J., et al. , Nature. 283, 583-585 (1980) McCormack, R. T., et al. , J. Immunol. 137, 1075-1082 (1986)