Anti-IFN gamma (Mouse) mAb Functional Grade
| Code | Size | Price |
|---|
| MBL-FP20712550 | 500 ug | £437.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: XMG1.2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Flow Cytometry
- Functional Study
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
IFN gamma
References
Knapp W., et al., Leukocyte typing IV. Oxford University Press (1989) Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Bullock, T. N., & Yagita, H., J Immunol. 174, 710-717 (2005)