Anti-IFN gamma (Mouse) mAb-Biotin
| Code | Size | Price |
|---|
| MBL-FP20713002 | 25 ug | £222.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: XMG1.2
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The XMG1.2 is a neutralizing antibody that binds with the mouse Interferon-gamma (IFN-γ) protein, a 15 -17 kDa cytokine with significant antibacterial, antiviral, and antitumoral properties. When secreted by natural killer cells and by natural killer T lymphocytes, it regulates the immune response and supports adaptive immunity when produced by Th1 or CD8+ T lymphocytes. IFN-γ plays an important role in the activation, the growth, and the differentiation of the macrophages, B and T lymphocytes, and natural killer cells. It interacts synergically with other cytokines, such as TNF-α, to inhibit proliferation of normal and transformed cells. IFN- γ is the primary cytokine that defines Th-1 cells.The biological activity of IFN-γ is not affected by glycosylation.
Concentration:
0.5 mg/mL
Conjugate:
Biotin
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
IFN gamma
References
Hemler, M. E., et al., J. Immunol. 132, 3011-3018 (1984) Schlossman, S. F., Leukocyte typing V. Oxford University Press (1995) Sanchez-Madrid, F., et al., Proc Natl Acad Sci U S A. 79, 7489-7493 (1982)