Anti-TIGIT (Mouse) mAb-PE
| Code | Size | Price |
|---|
| MBL-FP20746010 | 100 ug | £478.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 1G9
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 1G9 monoclonal antibody specifically binds to the mouse TIGIT, expressed on the T helper cells. While in humans it is expressed also on natural killer cells, Treg cells, memory CD4+ and CD8+ T lymphocytes. TIGIT is not expressed on B cells and is upregulated on CD4+ T cells following activation.TIGIT interacts with CD155, and mediates the interaction between natural killer cells or T lymphocytes with APC and fibroblasts and endothelial cells expressing PVR or PVR-like proteins.
Concentration:
0.2 mg/mL
Conjugate:
PE
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
TIGIT
References
Ledbetter, J. A., et al., Immunol Rev. 47, 63-90 (1979) Thomas, M. L., Annu Rev Immunol. 7, 339-369 (1989) Simon, D. I., et al., J Clin Invest. 105, 293-300 (2000)