Anti-Foxp3 (Mouse) mAb-FITC
| Code | Size | Price |
|---|
| MBL-FP20815010 | 100 ug | £594.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 3G3
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the ?scurfy? mice phenotype.
Concentration:
0.5 mg/mL
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Foxp3
References
Ledbetter, J. A., et al., Immunol Rev. 47, 63-90 (1979) Thomas, M. L., Annu Rev Immunol. 7, 339-369 (1989) Simon, D. I., et al., J Clin Invest. 105, 293-300 (2000)