Anti-Fc epsilon Receptor I alpha (FceR1) (Mouse) mAb-FITC
| Code | Size | Price |
|---|
| MBL-FP20845010 | 100 ug | £326.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: 41699
Regulatory Status: RUO
Target Species: Mouse
Application: Flow Cytometry
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
Concentration:
0.5 mg/mL
Conjugate:
FITC
Formulation:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Target:
Fc epsilon Receptor I alpha
References
Barclay, A., et al., The leucocyte antigen factsbook. Academic Press, London (1997) Pulendran, B., et al., J Immunol. 159, 2222-2231 (1997) Xin, K. Q., et al., J Virol. 80, 11899-11910 (2006)