Anti-CD8b (Rat) mAb Functional Grade
| Code | Size | Price |
|---|
| MBL-FP30042550 | 500 ug | £568.00 |
Quantity:
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Overview
Host Type: Mouse
Antibody Isotype: IgG1 κ
Antibody Clonality: Monoclonal
Antibody Clone: 341
Regulatory Status: RUO
Target Species: Rat
Applications:
- Flow Cytometry
- Functional Study
Shipping:
4°C
Storage:
4°C
Documents
Further Information
Background:
The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD8b
References
Shevach, E. M., Annu Rev Immunol. 18, 423-449 (2000) Wu, L., et al., Nature. 349, 71-74 (1991) Bliss, S. K., et al., J Immunol. 178, 7974-7983 (2007)