anti-ER-alpha (human), Rabbit Monoclonal (RM494)

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RevMab Biosciences
Product Code: REV-31-1386-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1386-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM494
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
Short-term: 4°C. Long-term: -20°C.

Images

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Immunohistochemical staining of formalin-fixed and paraffin-embedded human breast cancer tissue sections using anti-ER-alpha rabbit monoclonal antibody clone RM494 at a 1:100 dilution.
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Immunohistochemical staining of formalin-fixed and paraffin-embedded human breast cancer tissue sections using anti-ER-alpha rabbit monoclonal antibody clone RM494 at a 1:100 dilution.

Documents

Further Information

Alternate Names/Synonyms:
Estrogen Receptor
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freez/thaw cycles.
Immunogen:
Recombinant human ER-alpha.
Long Description:
Recombinant Antibody. This antibody reacts to human ER-alpha (Estrogen receptor). Isotype: Rabbit IgG. Immunogen: Recombinant human ER-alpha. Application: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer and osteoporosis.
NCBI Uniprot Number:
P03372
Package Type:
Vial
Product Description:
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer and osteoporosis.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human ER-alpha (Estrogen receptor).
Transportation:
Non-hazardous
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.