anti-CDX2 (human), Rabbit Monoclonal (RM495)
| Code | Size | Price |
|---|
| REV-31-1387-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM495
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Blue Ice
Storage:
Short-term: 4°C. Long-term: -20°C.
Documents
Further Information
Alternate Names/Synonyms:
Homeobox Protein CDX-2
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freez/thaw cycles.
Immunogen:
Recombinant human CDX2.
Long Description:
Recombinant Antibody. This antibody reacts to human CDX2. Isotype: Rabbit IgG. Immunogen: Recombinant human CDX2. Application: IHC. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 plays a role in early embryonic development of the intestinal tract and aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer. It is not expressed in the normal gastric mucosa. Loss of CDX2 protein expression has been correlated with loss of differentiation in colorectal cancers. CDX2 antibodies can be useful in distinguishing the gastrointestinal origin of metastatic adenocarcinomas and carcinoids.
NCBI Uniprot Number:
Q99626
Package Type:
Vial
Product Description:
CDX2 is a caudal-type homeobox gene that encodes an intestine-specific transcription factor expressed early in intestinal development and that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. CDX2 plays a role in early embryonic development of the intestinal tract and aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer. It is not expressed in the normal gastric mucosa. Loss of CDX2 protein expression has been correlated with loss of differentiation in colorectal cancers. CDX2 antibodies can be useful in distinguishing the gastrointestinal origin of metastatic adenocarcinomas and carcinoids.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CDX2.
Transportation:
Non-hazardous
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.