anti-CD68 (human), Rabbit Monoclonal (RM496)

RevMab Biosciences
Product Code: REV-31-1388-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1388-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM496
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
Short-term: 4°C. Long-term: -20°C.

Images

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Immunohistochemical staining of formalin-fixed and paraffin-embedded human tonsil tissue sections using anti-CD68 rabbit monoclonal antibody (clone RM496) at a 1:500 dilution.

Immunohistochemical staining of formalin-fixed and paraffin-embedded human tonsil tissue sections using anti-CD68 rabbit monoclonal antibody (clone RM496) at a 1:500 dilution.

Documents

Further Information

Alternate Names/Synonyms:
Macrosialin; GP110; Scavenger Receptor Class D Member 1; SCARD1
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freez/thaw cycles.
Immunogen:
Recombinant human CD68.
Long Description:
Recombinant Antibody. This antibody reacts to human CD68. Isotype: Rabbit IgG. Immunogen: Recombinant human CD68. Application: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies.
NCBI Uniprot Number:
P34810
Package Type:
Vial
Product Description:
CD68 [Macrosialin; GP110; SCARD1] is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML) and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several acute myeloid leukemia studies.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CD68.
Transportation:
Non-hazardous
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.