Recombinant Transmembrane Protein 173 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81615-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81615-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-9A7
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Transmembrane Protein 173
Background:
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
42kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100
Immunogen:
Recombinant protein of human TMEM173
ObservedMW:
40kDa
Purification method:
Affinity Purified
Target Synonym:
endoplasmic reticulum IFN stimulator;Endoplasmic reticulum interferon stimulator;ERIS;FLJ38577;hMITA;hSTING;Mediator of IRF3 activation;MITA;Mitochondrial mediator of IRF3 activation;MPYS;N terminal methionine proline tyrosine serine plasma membrane tetraspanner;NET23;Stimulator of interferon genes;Stimulator of interferon genes protein;STING;TM173;Tmem173;Transmembrane protein 173
UNIProt ID:
Q86WV6