Recombinant RENT1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81603-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81603-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R02-2E6
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RENT1
Background:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
124kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:3000 IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
A synthetic peptide of human RENT1
ObservedMW:
124kDa
Purification method:
Affinity Purified
Target Synonym:
ATP dependent helicase RENT1;ATP-dependent helicase RENT1;Delta helicase;FLJ43809;FLJ46894;HUPF 1;hUpf1;KIAA0221;Nonsense mRNA reducing factor 1;NORF 1;NORF1;pNORF 1;pNORF1;Regulator of nonsense transcripts 1;RENT 1;RENT1;RENT1;Smg 2;Smg 2 homolog nonsense mediated mRNA decay factor;UP Frameshift 1;Up frameshift mutation 1 homolog (S. cerevisiae);Up frameshift mutation 1 homolog;Up frameshift suppressor 1 homolog;Up-frameshift suppressor 1 homolog;UPF 1;UPF 1 regulator of nonsense transcripts homolog;upf1;UPF1 regulator of nonsense transcripts homolog;UPF1 RNA helicase and ATPase;Yeast Upf1p homolog
UNIProt ID:
Q92900