Recombinant Prohibitin Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81601-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81601-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R07-2G1
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Prohibitin
Background:
Prohibitin,also known as PHB,a member of the Band-7 family of proteins,is widely distributed in bacteria,plants,yeast,protozoa and mammals and is important in cell proliferation,differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria,where it acts as a chaperone protein,and is also found in the nucleus,where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB,which is a nuclear matrix protein,affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
30 kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human Prohibitin
ObservedMW:
30 kDa
Purification method:
Affinity Purified
Target Synonym:
Epididymis luminal protein 215;Epididymis secretory sperm binding protein Li 54e;HEL 215;HEL S 54e;PHB;PHB;PHB1;Prohibitin
UNIProt ID:
P35232