Recombinant mtTFA Monoclonal Antibody

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Elabscience
Product Code: E-AB-81584
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81584-50uL50uL£184.00
Quantity:
E-AB-81584-100uL100uL£251.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R08-3E2
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of mtTFA in paraffin-embedded Human breast cancer tissue using mtTFA Rabbit mAb at dilution 1:100
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Immunohistochemistry of mtTFA in paraffin-embedded Human breast cancer tissue using mtTFA Rabbit mAb at dilution 1:100

Documents

Further Information

Abbreviation:
mtTFA
Background:
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
29kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
A synthetic peptide of human mtTFA
ObservedMW:
24kDa
Purification method:
Affinity Purified
Target Synonym:
anscription factor 6-like 1;Mitochondrial transcription factor 1;mitochondrial transcription factor A;MtTF1;mtTFA;TCF 6;TCF-6;TCF6;TCF6L1;TCF6L2;TCF6L3;TFAM;TFAM;Transcription factor 6;Transcription factor 6 like 2 (mitochondrial transcription factor);Transcription factor 6 like 2;Transcription factor 6-like 2;transcription factor 6-like 3;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial precursor
UNIProt ID:
Q00059