Recombinant LC3A Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81578-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81578-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R05-1B6
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LC3A
Background:
LC3,also known as microtubule-associated protein 1 light chain 3 (MAP1LC3),is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A,LC3B,and LC3C. LC3 is first synthesized as pro-LC3,and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
14kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
A synthetic peptide of human MAP1LC3A
ObservedMW:
16kDa
Purification method:
Affinity Purified
Target Synonym:
ATG8E;Autophagy-related protein LC3 A;Autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3 like protein 1;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Map1lc3a;Microtubule associated proteins 1A/1B light chain 3;Microtubule-associated protein 1 light chain 3 alpha;Microtubule-associated proteins 1A and 1B;light chain 3;Microtubule-associated proteins 1A/1B light chain 3A;MLP3A
UNIProt ID:
Q9H492
References
- https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full