Recombinant Lamin A/C Monoclonal Antibody

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Elabscience
Product Code: E-AB-81577
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81577-50uL50uL£184.00
Quantity:
E-AB-81577-100uL100uL£251.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R07-1I5
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot detection of Lamin A/C in U251,Lncap,A549 using Lamin A/C Rabbit mAb(1:1000 diluted)
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Immunohistochemistry of Lamin A/C in paraffin-embedded Human breast cancer tissue using Lamin A/C Rabbit mAb at dilution 1:50
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Western blot detection of Lamin A/C in U251,Lncap,A549 using Lamin A/C Rabbit mAb(1:1000 diluted)
Immunohistochemistry of Lamin A/C in paraffin-embedded Human breast cancer tissue using Lamin A/C Rabbit mAb at dilution 1:50

Documents

Further Information

Abbreviation:
Lamin A/C
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
74 kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human Lamin A/C
ObservedMW:
74/63 kDa
Purification method:
Affinity Purified
Target Synonym:
70 kDa lamin;Cardiomyopathy dilated 1A (autosomal dominant);CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;Lamin A;Lamin A/C;Lamin A/C like 1;Lamin;Lamin C;Lamin-A/C;LDP1;LFP;LGMD1B;Limb girdle muscular dystrophy 1B (autosomal dominant);LMN 1;LMN A;LMN C;LMN1;LMNA;LMNA;LMNC;LMNL1;Prelamin A/C;PRO1;Renal carcinoma antigen NY REN 32;Renal carcinoma antigen NY-REN-32;Renal carcinoma antigen NYREN32
UNIProt ID:
P02545