Recombinant IMPDH2 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81572-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81572-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-1B8
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IMPDH2
Background:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
56kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human IMPDH2
ObservedMW:
56kDa
Purification method:
Affinity Purified
Target Synonym:
IMDH2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase 2;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH II;IMPDH-II;Impdh2;Inosine 5' monophosphate dehydrogenase 2;Inosine 5' phosphate dehydrogenase 2;Inosine monophosphate dehydrogenase type II;Inosine-5''-monophosphate dehydrogenase 2
UNIProt ID:
P12268