Recombinant Cofilin Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81548-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81548-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-2C0
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Cofilin
Background:
Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility,cytokinesis,and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity,also causing translocation from the nucleus to the cytoplasm.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
19kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
Immunogen:
A synthetic peptide of human Cofilin
ObservedMW:
19kDa
Purification method:
Affinity Purified
Target Synonym:
18 kDa phosphoprotein;CFL 1;CFL;CFL1;COF1;Cofilin 1;Cofilin 1 non muscle;Cofilin;Cofilin non muscle isoform;Cofilin-1;epididymis secretory protein Li 15;HEL-S-15;non-muscle isoform;p18
UNIProt ID:
P23528