Recombinant APC Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81529-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81529-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-2E4
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
APC
Background:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
312kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
A synthetic peptide of human APC
ObservedMW:
160kDa
Purification method:
Affinity Purified
Target Synonym:
Adenomatous Polyposis Coli;Adenomatous polyposis coli protein;Apc;APC;CC1;Deleted in polyposis 2.5;DP2;DP2.5;DP3;FAP;FPC;GS;Protein APC
UNIProt ID:
P25054