Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81528-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81528-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R07-1I6
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Angiotensin II Type 1 Receptor
Background:
Angiotensin II (Ang II),the main effector molecule of the renin-angiotensin system,exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1,also named as AT1R),thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone,cardiovascular function,salt and water homeostasis,AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease,from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
41kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
A synthetic peptide of human Angiotensin II Type 1 Receptor
ObservedMW:
41kDa
Purification method:
Affinity Purified
Target Synonym:
AGTR1;AG2S;AGTR1B;AT1;AT1AR;AT1B;AT1BR;AT1R;AT2R1;HAT1R
UNIProt ID:
P30556