Recombinant Keap1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81505-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81505-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R02-1H7
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Keap1
Background:
KEAP1,also named as INRF2,KIAA0132 and KLHL19,is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase,which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2,the
ETGE and DLG sites,which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
70kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:20-1:50
Immunogen:
Recombinant protein of human Keap1
ObservedMW:
60/64kDa
Purification method:
Affinity Purified
Target Synonym:
Cytosolic inhibitor of Nrf2;INrf 2;INrf2;Keap 1;KEAP1;KEAP1;Kelch like ECH associated protein 1;Kelch like family member 19;Kelch like protein 19;Kelch-like ECH-associated protein 1;Kelch-like protein 19;KIAA0132;KLHL 19;KLHL19;MGC10630;MGC1114;MGC20887;MGC4407;MGC9454
UNIProt ID:
Q14145