Recombinant Dnmt3a Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81503-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81503-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R03-8H4
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Dnmt3a
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
102kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
A synthetic peptide of human Dnmt3a
ObservedMW:
130kDa
Purification method:
Affinity Purified
Target Synonym:
DNA (cytosine 5) methyltransferase 3 alpha;DNA (cytosine 5) methyltransferase 3A;DNA (cytosine-5)-methyltransferase 3A;DNA cytosine methyltransferase 3A2;DNA methyltransferase 3 alpha;DNA methyltransferase 3a;DNA methyltransferase HsaIIIA;DNA MTase HsaIIIA;DNM3A;DNMT 3a;DNMT;Dnmt3a;DNMT3A2;M.HsaIIIA;MCMT;OTTHUMP00000201149;TBRS
UNIProt ID:
Q9Y6K1