Recombinant TriMethyl-Histone H3 Monoclonal Antibody

Elabscience
Product Code: E-AB-81497
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81497-50uL50uL£184.00
Quantity:
E-AB-81497-100uL100uL£251.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R01-8I4
Regulatory Status: RUO
Target Species:
  • Human
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemical of TriMethyl-Histone H3 (Lys27) in Human lung cancer tissue using TriMethyl-Histone H3 (Lys27) antibody at dilution 1:20

Immunohistochemical of TriMethyl-Histone H3 (Lys27) in Human lung cancer tissue using TriMethyl-Histone H3 (Lys27) antibody at dilution 1:20

Documents

Further Information

Abbreviation:
TriMethyl-Histone H3
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
15kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
A synthetic methyl-peptide corresponding to residues surrounding Lys27 of human Histone H3
ObservedMW:
15kDa
Purification method:
Affinity Purified
Target Synonym:
H3 histone family;member A;H3/A;H31;H3FA;Hist1h3a;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E;HIST1H3F;HIST1H3G;HIST1H3H;HIST1H3I;HIST1H3J;histone 1;H3a;Histone cluster 1;H3a;Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l
UNIProt ID:
P68431