Recombinant VEGF Receptor 1 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81493-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81493-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-1A4
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
VEGF Receptor 1
Background:
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
151kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human VEGF Receptor 1
ObservedMW:
180kDa
Purification method:
Affinity Purified
Target Synonym:
EC 2.7.10.1;FLT 1;FLT;Flt-1;FLT1;Fms like tyrosine kinase 1;Fms related tyrosine kinase 1;Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor);Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor;Fms-like tyrosine kinase 1;FRT;Soluble VEGF receptor 1 14;Soluble VEGFR1 variant 2;Soluble VEGFR1 variant 21;Tyrosine protein kinase FRT;Tyrosine protein kinase receptor FLT;Tyrosine-protein kinase FRT;Tyrosine-protein kinase receptor FLT;Vascular endothelial growth factor receptor 1;Vascular endothelial growth factor vascular permeability factor receptor;Vascular permeability factor receptor 1;Vascular permeability factor receptor;VEGFR 1;VEGFR-1;VEGFR1;VGFR1
UNIProt ID:
P17948