Recombinant ILF3 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81475-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81475-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R04-3C1
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ILF3
Background:
This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
95kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:5000 IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
A synthetic peptide of human ILF3
ObservedMW:
95kDa
Purification method:
Affinity Purified
Target Synonym:
CBTF;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;DRBF;DRBP76;ILF3;ILF3;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;MPHOSPH4;MPP4;NF AT 90;NF-AT-90;NF110;NF90;NFAR;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;TCP80;Translational control protein 80
UNIProt ID:
Q12906