Recombinant GSDMD Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81473-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81473-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-5C5
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GSDMD
Background:
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently,GSDMD is identified as a new component of inflammasomes,and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
53kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant protein of human GSDMD
ObservedMW:
53kDa
Purification method:
Affinity Purified
Target Synonym:
DF5L;DFNA5L;FKSG10;GSDMDC1;GSDMD
UNIProt ID:
P57764