Recombinant FTO Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81470-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81470-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-8G5
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FTO
Background:
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
58kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-5000 IHC 1:50-1:100 IF 1:20-1:100
Immunogen:
A synthetic peptide of human FTO
ObservedMW:
58kDa
Purification method:
Affinity Purified
Target Synonym:
AlkB homolog 9;ALKBH9;Alpha-ketoglutarate-dependent dioxygenase FTO;AW743446;Fat mass and obesity-associated protein;FATSO;MOUSE;HOMOLOG OF;Fto;FTO;GDFD;KIAA1752;mKIAA1752;Protein fatso
UNIProt ID:
Q9C0B1