Recombinant FAK Monoclonal Antibody

Elabscience
Product Code: E-AB-81468
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81468-50uL50uL£184.00
Quantity:
E-AB-81468-100uL100uL£251.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R06-6B6
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot detection of FAK in K562,C6,3T3,Hela cell lysates using FAK Rabbit mAb(1:1000 diluted).Predicted band size:119kDa.Observed band size:125kDa.
2 / 2
Immunohistochemistry of FAK in paraffin-embedded Human colon cancer tissue using FAK Rabbit mAb at dilution 1:50

Western blot detection of FAK in K562,C6,3T3,Hela cell lysates using FAK Rabbit mAb(1:1000 diluted).Predicted band size:119kDa.Observed band size:125kDa.
Immunohistochemistry of FAK in paraffin-embedded Human colon cancer tissue using FAK Rabbit mAb at dilution 1:50

Documents

Further Information

Abbreviation:
FAK
Background:
FAK (Focal adhesion kinase 1) is also named as FAK1,FADK,pp125FAK,FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion,migration,proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator',controlling and coordinating cellular responses that include cell migration,survival,proliferation and,epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
119kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human FAK
ObservedMW:
125kDa
Purification method:
Affinity Purified
Target Synonym:
FADK 1;FADK;FAK related non kinase polypeptide;FAK1;FAK1;Focal adhesion kinase 1;Focal adhesion Kinase;Focal adhesion kinase isoform FAK Del33;Focal adhesion kinase related nonkinase;FRNK;p125FAK;pp125FAK;PPP1R71;Protein phosphatase 1 regulatory subunit 71;Protein tyrosine kinase 2;Protein-tyrosine kinase 2;Ptk2;PTK2 protein tyrosine kinase 2
UNIProt ID:
Q05397