Recombinant Estrogen Receptor alpha Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81467-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81467-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R05-1E4
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Estrogen Receptor alpha
Background:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
66kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100 IF 1:20-1:100
Immunogen:
A synthetic peptide of human Estrogen Receptor alpha
ObservedMW:
66kDa
Purification method:
Affinity Purified
Target Synonym:
DKFZp686N23123;ER alpha;ER;ER-alpha;Era;ESR;ESR1;ESR1;ESRA;Estradiol receptor;Estrogen nuclear receptor alpha;Estrogen receptor 1;Estrogen receptor alpha 3*;4;5;6;7*/822 isoform;Estrogen receptor alpha;Estrogen receptor alpha delta 3*;4;5;6;7*;8*/941 isoform;Estrogen receptor alpha delta 3*;4;5;6;7*/819 2 isoform;Estrogen receptor alpha delta 4 +49 isoform;Estrogen receptor alpha delta 4*;5;6;7*/654 isoform;Estrogen receptor alpha delta 4*;5;6;7;8*/901 isoform;Estrogen receptor alpha E1 E2 1 2;Estrogen receptor alpha E1 N2 E2 1 2;Estrogen receptor;ESTRR;NR3A1;Nuclear receptor subfamily 3 group A member 1
UNIProt ID:
P03372