Recombinant Cyclooxygenase 2 Monoclonal Antibody

Elabscience
Product Code: E-AB-81464
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81464-50uL50uL£184.00
Quantity:
E-AB-81464-100uL100uL£251.00
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Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R04-3I1
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot detection of COX-2/cyclooxygenase-2 in Rat Brain lysates using COX-2/cyclooxygenase-2 Rabbit mAb(1:500 diluted).Predicted band size:69kDa.Observed band size:69kDa.
2 / 2
Immunohistochemistry of COX2 in paraffin-embedded Human lung cancer tissue using COX2 Rabbit mAb at dilution 1:50

Western blot detection of COX-2/cyclooxygenase-2 in Rat Brain lysates using COX-2/cyclooxygenase-2 Rabbit mAb(1:500 diluted).Predicted band size:69kDa.Observed band size:69kDa.
Immunohistochemistry of COX2 in paraffin-embedded Human lung cancer tissue using COX2 Rabbit mAb at dilution 1:50

Documents

Further Information

Abbreviation:
Cyclooxygenase 2
Background:
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
69kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human COX2
ObservedMW:
69kDa
Purification method:
Affinity Purified
Target Synonym:
COX 2;COX-2;COX2;Cyclooxygenase 2;Cyclooxygenase 2b;Cyclooxygenase;Cyclooxygenase-2;Cyclooxygenase2;EC 1.14.99.1;fj02a10;Glucocorticoid-regulated inflammatory cyclooxygenase;Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase;GRIPGHS;hCox 2;Macrophage activation-associated marker protein P71/73;OTTHUMP00000033524;PES-2;PGG/HS;PGH synthase 2;PGH2;PGHS 2;PGHS-2;PGHS2;PHS 2;PHS II;PHS2;Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase);Prostaglandin endoperoxide synthase 2;Prostaglandin G/H synthase 2;Prostaglandin G/H synthase 2 precursor;Prostaglandin G/H synthase and cyclooxygenase;Prostaglandin G/H synthase;Prostaglandin H2 synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase);Prostaglandin-endoperoxide synthase 2;PTGS2;ptgs2a;TIS10;TIS10 protein;unp1239;wu:fj02a10
UNIProt ID:
P35354

References

  • https://www.sciencedirect.com/science/article/pii/S1043661822002286
  • https://www.sciencedirect.com/science/article/pii/S0024320521012686
  • https://www.nature.com/articles/s41598-022-04785-z
  • https://www.sciencedirect.com/science/article/pii/S037887411731841X
  • https://www.sciencedirect.com/science/article/pii/S0305417921000978
  • https://link.springer.com/article/10.1007/s12012-023-09780-y
  • https://link.springer.com/article/10.1007/s11356-019-05420-7
  • https://link.springer.com/article/10.1186/s12917-020-02448-7