Recombinant Cytochrome C Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81449-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81449-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R09-6H3
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Cytochrome C
Background:
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
12kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000 IHC 1:50-1:100
Immunogen:
A synthetic peptide of human Cytochrome C
ObservedMW:
14kDa
Purification method:
Affinity Purified
Target Synonym:
Cytochrome C;Somatic;CYC;Cytochrome C;THC4;HCS
UNIProt ID:
P99999
References
- https://onlinelibrary.wiley.com/doi/abs/10.1111/and.14185