Recombinant ERK2 Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81446-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81446-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R07-1A9
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ERK2
Background:
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
41kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:20-1:100 IF 1:50-1:100
Immunogen:
A synthetic peptide of human ERK2
ObservedMW:
41kDa
Purification method:
Affinity Purified
Target Synonym:
ERK 2;ERK;ERK-2;ERT1;Extracellular Signal Regulated Kinase 2;Extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;Mapk1;MAPK2;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;MK01;P38;P40;P41;p42-MAPK;P42MAPK;PRKM1;PRKM2;protein kinase;mitogen-activated;1;protein kinase;mitogen-activated;2;protein tyrosine kinase ERK2
UNIProt ID:
P28482