Recombinant c Myc Monoclonal Antibody
| Code | Size | Price |
|---|
| E-AB-81443-50uL | 50uL | £184.00 |
Quantity:
| E-AB-81443-100uL | 100uL | £251.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R05-5E2
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
c Myc
Background:
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
49kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000
Immunogen:
A synthetic peptide of human c-Myc
ObservedMW:
57-65kDa
Purification method:
Affinity Purified
Target Synonym:
AU016757;Avian myelocytomatosis viral oncogene homolog;bHLHe39;c Myc;Class E basic helix-loop-helix protein 39;MRTL;Myc;Myc protein;Myc proto oncogene protein;Myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYC;Myc2;MYCC;Myelocytomatosis oncogene;Niard;Nird;Oncogene Myc;OTTHUMP00000158589;Proto-oncogene c-Myc;Protooncogene homologous to myelocytomatosis virus;RNCMYC;Transcription factor p64;Transcriptional regulator Myc-A;V-Myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog (avian)
UNIProt ID:
P01106