Recombinant PI3 Kinase p85 alpha Monoclonal Antibody

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Elabscience
Product Code: E-AB-81435
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-81435-50uL50uL£184.00
Quantity:
E-AB-81435-100uL100uL£251.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Monoclonal
Antibody Clone: R03-3C7
Regulatory Status: RUO
Target Species:
  • Hamster
  • Human
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence of PI3 Kinase p85 alpha (green) in MCF-7 using PI3 Kinase p85 alpha antibody at dilution 1:20, and DAPI(blue)
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Immunofluorescence of PI3 Kinase p85 alpha (green) in MCF-7 using PI3 Kinase p85 alpha antibody at dilution 1:20, and DAPI(blue)

Documents

Further Information

Abbreviation:
PI3 Kinase p85 alpha
Background:
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Calculated MW:
84kDa
Concentration:
300 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IF 1:20-1:100
Immunogen:
A synthetic peptide of human PI 3 Kinase p85 alpha
ObservedMW:
84kDa
Purification method:
Affinity Purified
Target Synonym:
GRB1;p85 alpha;p85;P85A;Phosphatidylinositol 3 kinase associated p 85 alpha;Phosphatidylinositol 3 kinase regulatory 1;Phosphatidylinositol 3 kinase;regulatory subunit;polypeptide 1 (p85 alpha);Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphoinositide 3 kinase;regulatory subunit 1 (alpha);PI3 kinase p85 subunit alpha;PI3-kinase regulatory subunit alpha;PI3-kinase subunit p85-alpha;PI3K;PI3K regulatory subunit alpha;Pik3r1;PtdIns 3 kinase p85 alpha;PtdIns-3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha
UNIProt ID:
P27986