Recombinant Human/Mouse/Rat GDF-8/Myostatin
| Code | Size | Price |
|---|
| PKSM041399-10ug | 10ug | £386.00 |
Quantity:
| PKSM041399-50ug | 50ug | £1,005.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mixed
Regulatory Status: RUO
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Further Information
Abbreviation:
GDF-8;Myostatin
Accession:
O14793
Background:
Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
Calculated MW:
13.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
12-15 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Lys262-Ser375
Target Synonym:
Growth/differentiation factor 8;GDF-8;Myostatin;Mstn;Gdf8
UNIProt ID:
O14793